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<B>Comparison of risk for institutionalization for patients with and without
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   Lead Investigator:    Courtney O'Neill
   Institution      :    Medical Univ of South Carolina
   E-Mail           :    oneillc@musc.edu
   Proposal ID      :    543
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   Proposal Description:
   <textarea name="description" rows="12" cols="85" wrap="virtual" readonly>The main objective of this project is to understand the diabetes treatments       represented among normal, cognitively impaired, and individuals with              Alzheimer???s disease within the NACC database. The goal of this project is to    examine institutionalization rates among normal individuals, cognitively          impaired individuals, and individuals diagnosed with Alzheimer???s disease.       Specifically, the research team will conduct a multiple logistic regression       analysis to assess risk factor related to institutionalization rates for          individuals with and without diabetes treatment as well as a time to              institutionalization analysis (survival/proportional hazards regression).The      research team will use this dataset to examine the historical effect of           diabetic medications for signals that diabetic medications slow cognitive         decline. The research team will evaluate progression to cognitive impairment,     progression to Alzheimer???s disease, progression to institutionalization in      correlation to diabetes pharmaceutical treatment, and associations with           activities of daily living. </textarea>